The Piccolo Hotel provides easy access to Bukit Bintang with its location between Lot 10 Shopping Mall and Starhill Gallery, while facing the Pavilion Shopping Mall across the street. At its doorsteps is the Bintang Walk, a stretch of street where fancy cafes, bars and restaurants provide lively nightly entertainment and excellent dining opportunities.

Suria KLCC Shopping Mall, the Petronas Twin Towers, KL Tower and KL Convention Center can be reached by walking for a moderate distance, though you can use the LRT train instead from the Bukit Bintang Monorail Station, which is a very short distance away from the hotel. Taxis and buses are easily available all around the area. From the Kuala Lumpur International airport, the hotel can be reached in about 45 minutes while a train ride from the KL Sentral Station will only take between 5 to 8 minutes.